Honors College Capstone Experience/Thesis Projects

Department

Biology

Additional Departmental Affiliation

Chemistry

Document Type

Thesis

Abstract

In the present study, we report the green synthesis of gold nanoparticles (GNPs), using potato starch as a reducing as well as a stabilizing agent in an aqueous buffer medium. The resulting starch-GNPs (St-GNPs) were near spherical in shape with an average diameter of 15 ± 5 nm. In this approach, St-GNPs were characterized and investigated for their antibacterial properties against both gram negative (Escherichia coli) and gram positive (Staphylococcus epidermidis) bacteria. These St-GNPs were found to possess significant dose dependent antibacterial activity against bacteria. Also, St-GNPs showed a significant catalytic activity and can easily be functionalized using a simple, greener method for various applications in non-polar solvent. The overall results suggest the synthesis of multifunctional St-GNPs, which can be used as an antibacterial agent, catalyst and for a wide variety of environmental, biomedical, and industrial chemical applications.

Advisor(s) or Committee Chair

Dr. Rajalingam Dakshinamurthy

Disciplines

Cell Biology | Chemical Actions and Uses | Chemicals and Drugs | Medical Biochemistry | Medical Sciences | Pathology

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