Publication Date

12-2010

Advisor(s) - Committee Chair

Dr. Qi Li (Director), Dr. Guangming Xing, Dr. James Gary

Degree Program

Department of Mathematics and Computer Science

Degree Type

Master of Science

Abstract

Stages in Drosophila development denote the time after fertilization at which certain specific events occur in the developmental cycle. Stage information of a host embryo, as well as spatial information of a gene expression region is indispensable input for the discovery of the pattern of gene-gene interaction. Manual labeling of stages is becoming a bottleneck under the circumstance of high throughput embryo images. Automatic recognition based on the appearances of embryos is becoming a more desirable scheme. This problem, however, is very challenging due to severe variations of illumination and gene expressions. In this research thesis, we propose an appearance based recognition method using orientation histograms and Gabor filter. Furthermore, we apply Principal Component Analysis to reduce the dimension of the low-level features, aiming to accelerate the speed of recognition. With the experiments on BDGP images, we show the promise of the proposed method.

Disciplines

Computational Biology | Genetics | Numerical Analysis and Scientific Computing