•  
  •  
 

OVERFEEDING INFLUENCES METABOLISM, APPETITE, SATIETY, AND CALORIC INTAKE IN OBESE-PRONE AND OBESE-RESISTANT INDIVIDUALS

Abstract

PURPOSE: This project explored how self-reported appetite and satiety, resting metabolic rate, caloric intake, and appetite-regulating hormones are affected by a single overfeeding period in obese-prone and obese-resistant individuals. METHODS: Adult men and women (n = 12; 22 ± 2 yr) participated in this study. Participants were grouped into OP (n = 5 ) and OR (n = 7) using self-reporting and family history, BMI, and body composition assessment. Participants’ resting metabolic rate (RMR) and body composition were assessed during their initial visit to the lab (V1). During visit two (V2), participants self-reported their appetite and satiety, and a five mL blood sample was collected. Participants consumed candy ad libitum for 30 minutes (overfeeding meal) and then self-reported their post-meal appetite and satiety. An additional five mL blood sample was collected 30 minutes after the meal ended. Participants returned the morning after V2 for their third visit (V3). Participants self-reported their appetite and satiety, a five mL blood sample was collected, and a second RMR assessment was completed. Differences in reported appetite and satiety, RMR, 24-hr caloric intake, ghrelin, insulin, and GLP-1 between visits were analyzed using a two-factor (treatment x time), repeated measures ANOVA followed by Bonferroni post-hoc testing. Differences in variables between OP and OR within each timepoint were determined using independent-samples t-tests. All data are reported as mean ± standard deviation, and a was set at p ≤ .05. RESULTS: Body fat percentage was different between OP and OR (29.9% and 14.8%, respectively; p = .004). Self-reported appetite decreased post-meal in both OP and OR (-66% and -62%, respectively; p < .001). Self-reported satiety increased post-meal in both OP and OR (+48.8% and 112%, respectively; p < .001). Post-meal satiety was 28.8% higher in OR than OP (p = .037). There was an overall effect for RMR between OP and OR (p = .014), however, RMR at V1 and V3 was not different between OP and OR. 24-hr caloric intake was not different between OP and OR. CONCLUSION: Both groups reported a decrease in appetite and an increase in satiety post-meal, with OR reporting significantly higher satiety levels. Obese-resistant individuals may experience greater perceived satiety in response to an overfeeding meal.

This document is currently not available here.

Share

COinS