Ban Abbas1, Nawfel Abdulameer2, Waqar Zuberi2Bini Moorthy2, Joseph Wier3FACSM

1IQIVA, Overland Park, KS; 2Medical School UMKC, Kansas City, MO; 3Kansas University,Lawrence KS.

PURPOSE: Serious Mental Illness includes diseases like MDD, anxiety, and personality disorder, affect 1 in 20 Americans. Those afflicted with such disorders are more likely to have metabolic dysfunction and earlier mortality. Current pharmaceutical regimens are associated with adverse reactions that can worsen long-term health outcomes, particularly regarding metabolic function. METHODS: We searched MEDLINE, Psychology, and Behavioral Sciences Collection, PsycINFO, and PubMed without language restrictions which are available, using the key words: ((exercise OR physical activities OR physical training) AND (serious mental illness)). After determined potentially eligible articles. We included articles in this meta-analysis were studies that: (1) Investigated adult participants with serious mental illness (2) Study that indicated a meta-analysis and review (3) planned, structured, repetitive, and purposive physical activity in one arm and other arm was either control patient who has disease with or without regular method of treatment as medication or psychotherapy. RESULTS: New investigations into non-medicinal options do indicate positive outcomes without the negative side effects. In particular, exercise has been associated with reduced depressive episodes, schizophrenic symptoms, and anxiety; with the added benefit of improved general health. Research indicates that the poor allocation of resources towards standardized and flexible exercise protocols has prevented the universal expansion of this adjunct therapy in any meaningful way, in spite of its recognized benefits. CONCLUSION: To reiterate these observations, we had organized a project consisting of reasonable exercise sessions for five-times/week over a twelve-week timeframe. These sessions will consist of 5-10-minute warm-ups, 30 mins of aerobics, 15 minutes of resistance training, and 5-10-minute cool down. One session will last for 1 hour, overall. The participants involved will also be providing valuable input for scheduling sessions and for techniques to increase motivation.

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