Polly Montgomery,a,b Ming Wang,a Biyi Shen,a Federico Silva-Palacios,b Ana Casanegra,b,c Shangming Zhang,a William Pomilla,a Omar L. Esponda,b,d Marcos Kuroki,a Andrew Gardner,a,b

aPenn State College of Medicine, Hershey, PA; bUniversity of Oklahoma Health Sciences Center, Oklahoma City, OK; cMayo Clinic, Rochester, MN; dHospital Perea, Mayaguez, Puerto Rico.

Peripheral Artery Disease (PAD) is a circulatory condition in which narrowed blood vessels reduce blood flow to the limbs. Many individuals with PAD may not have access or interest in participating in formal structured exercise programs, but they could nevertheless benefit by incorporating a greater amount of walking into their daily routine. PURPOSE: We compared the prevalence of participants with and without PAD who meet the recommendations of attaining more than 7,000 and 10,000 steps/day, and we determined whether PAD status was significantly associated with meeting the daily step count recommendations before and after adjusting for demographic variables, comorbid conditions, and cardiovascular risk factors. METHODS: Participants with PAD (n=396) and those without PAD (n=396) who were matched on age and sex were assessed on their walking for seven consecutive days with a step activity monitor attached to the ankle. RESUTS: The PAD group took significantly fewer steps/day than the non-PAD control group (6,722±3,393 vs. 9,475±4,110 steps/day; p<0.001). Only 37.6% and 15.7% of the PAD group attained the recommendations of walking for at least 7,000 and 10,000 steps/day, respectively, whereas 67.9% and 37.4% of the control group attained these recommendations (p<0.001 for each recommendation). In multivariable logistic regression models, having PAD was associated with a 62% lower chance of attaining 7,000 steps/day than compared to the control group (OR=0.383, 95% CI= 0.259-0.565, p<0.001), and a 55% lower chance of attaining 10,000 steps/day (OR=0.449, 95% CI=0.282-0.709, p<0.001). Significant covariates (p<0.01) included age, current smoking, diabetes, and body mass index (only for the 10,000 step/day recommendation). CONCLUSIONS: Participants with PAD had a 29% lower daily step count compared to age- and sex-matched controls, and were less likely to attain the 7,000 and 10,000 steps/day recommendations. Additionally, participants who were least likely to meet the 7,000 and 10,000 daily step count recommendations included those who were older, currently smoked, had diabetes, and had higher body mass index.

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