Ox66TM claims to be the only solid form of oxygen known to be in existence. It is an aluminum hydroxide clathrate that can trap oxygen molecules within its structure and when digested the oxygen molecules can be absorbed into the portal bloodstream. It has previously been implemented in clinical settings to reduce hypoxia related medical conditions. However, it is currently unknown whether Ox66TM has an effect on performance measures at or near the ventilatory threshold during high intensity exercise. PURPOSE: The purpose of this study was to evaluate the ergogenic impact of acute Ox66TM ingestion on submaximal aerobic performance measures and ventilatory threshold during exercise testing using Bruce protocol. METHODS: 36 college age participants (20 males and 16 females) were recruited to complete this study. Participants attended three testing sessions. During the first session, baseline measurements were acquired and participants were familiarized with the testing procedures. During the second and third tests participants were randomized to receive either a placebo or the Ox66TM supplement. Heart rate, ventilatory threshold, respiratory exchange ratio and rating of perceived exertion (RPE) were recorded throughout each test. RESULTS: Overall there were no consistent differences between the placebo and Ox66TM conditions for all participants combined. However, when men and women were evaluated separately, there were a few significant differences. Under the Ox66TM condition men had a slightly higher VO2 (p=0.045) and higher heart rate (p=0.046) at ventilatory threshold. Women had a slightly lower RPE (p=0.047) at ventilatory threshold with the Ox66TM supplement. CONCLUSION: Ox66TM supplementation resulted in small improvements in a few submaximal aerobic performance measures. Although these results are statistically significant, it is unlikely that Ox66TM supplementation actually causes ergogenic performance benefits.



To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.