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THE IMPACT OF A HIGH FIBER DIET ON PULSE WAVE VELOCITY IN YOUNG ADULTS AT RISK FOR CARDIOVASCULAR DIESEASE

Abstract

Christa Michelle Bazemore, Lauren C. Bates, Lee Stoner, FACSM. University of North Carolina - Chapel Hill, Chapel Hill, NC.

BACKGROUND: Cardiovascular disease (CVD) is the leading cause of death globally. CVD risk is increased through poor diet, particularly when the diet is low in fiber. High fiber diets have been recommended to reduce CVD risk and all-cause mortality. However, it is unclear whether increasing fiber intake can improve subclinical cardiovascular outcomes in asymptomatic individuals, i.e., decreased CVD risk. The purpose of this study is to evaluate whether a high fiber diet reduces aortic arterial stiffness (AS), measured using carotid-femoral pulse wave velocity (PWV), in young adults (20-35 years) at risk for CVD. METHODS: Our proposed 8-week randomized control trial will include young (20-35 years) male and female adults (n=60), at high risk for CVD. American College of Sports Medicine risk stratification scoring including age, family history, smoking status, sedentary lifestyle, obesity, dyslipidemia, prediabetes, and dietary patterns (meal number, food group consumption, snacking habits) will be utilized to classify CVD risk. Eligible moderate to high-risk participants will be randomized into three groups including one control and two experimental groups. The control group (n=20) will be instructed to continue their normal dietary pattern. One experimental group will increase fiber intake (45 g) in addition to their normal diet (n=20). The second experimental group will substitute fiber (45 g) for isocaloric foods from their normal diet (n=20). At baseline, 4-week, and 8-week timepoints, PWV will be measured. A linear mixed model will be used to assess the group and time differences in PWV across the duration of the study. ANTICIPATED RESULTS: We hypothesize that the implementation of a high fiber diet, whether this be as an addition to one’s normal diet or as a substitution will reduce PWV after 8-weeks. A 1 m/s decrease in PWV will be considered a clinically significant CVD risk reduction. Our proposed study will potentially lead to improvements in dietary recommendations to improve AS in young adults at risk for CVD.

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