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THE EFFECT OF ACUTE AGMATINE SULFATE SUPPLEMENTATION ON REPEATED ANAEROBIC SPRINT PERFORMANCE

Abstract

Cliff Helton, Luke Middleton, Justin Moody, Christopher G. Ballmann, FACSM, Tyler D. Williams, Rebecca R. Rogers. Samford University, Birmingham, AL.

BACKGROUND: Agmatine sulfate is a commonly used ingredient in many pre-workout supplement blends that aim to improve physical performance and energy levels while exercising. However, the effect of isolated agmatine sulfate supplementation on anaerobic exercise performance is unknown. Therefore, the purpose of this study is to investigate the effect of acute agmatine sulfate supplementation on repeated anaerobic sprint performance. METHODS: Physically active, college-age males (21.8±0.5 yrs, 169.5±27.1 lbs, 69.0±5.0 in) were recruited into the study. The study was approved by the university Institutional Review Board. All participants completed a health history and informed consent. Participants visited our laboratory two times and completed three 15-second Wingate Anaerobic Cycling Tests (WAnT) at 7.5% of body weight after consuming either two 500 mg capsules of agmatine sulfate or two 500 mg placebo (corn starch) capsules 30 mins prior to exercise. There was a 2-minute recovery break between each WAnT. Blood lactate was measured before and after the 3x15 WAnT tests and rate of perceived exertion (RPE) was recorded. The agmatine sulfate and placebo trials were randomized and counterbalanced. Each visit was separated by a 72-hour washout period. RESULTS: Mean watts (p=0.44), peak watts (p=0.93), anaerobic capacity (p=0.42), anaerobic power (p=0.97), fatigue index (p=0.77), heart rate (p=0.31), blood lactate (p=0.40) and RPE (p=0.24) were averaged over the three repeated WAnTs and were not significantly different between the agmatine sulfate and placebo conditions. CONCLUSION: These findings do not support consuming one dose agmatine sulfate supplementation prior to exercise to improve anaerobic exercise performance or perceived exertion.

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