Article Title



Chloe Bagdonas, Gaven A. Barker, Alyssa L. Parten, Hunter S. Waldman. University of North Alabama, Florence, AL.

BACKGROUND: Skeletal muscle damage resulting in delayed-onset muscle soreness (DOMS) is common following strenuous exercise and dietary supplements are on strategy to mitigate DOMS. Astaxanthin (AX) is a dietary supplement that has been shown to enhance cell membrane stability and suppress inflammation. However, data in humans are limited and therefore, the purpose of this study is to examine the impact of AX supplementation (12 mg/day) for 4-weeks on subjective markers of DOMS following an extensive muscle damage protocol. METHODS: Participants will be recreationally active males (age, 18-35 years) with an accumulation of 1-5 hours a week of aerobic and/or resistance-based exercise participation. Two-weeks prior to the study, antioxidant and creatine supplementation will be eliminated. Additionally, no caffeine or alcohol will be consumed 48 hours prior to each testing session. Participants will report to the laboratory on five visits in a double-blinded, between study design. Visit 1 will include completion of an informed consent and the collection of anthropometric data and a daily training/nutrition log. During visit 2, participants will complete an indirect 1-repetition maximum (RM) on the leg press. Participants will then complete 5 sets of 10 reps of at 60% of their 1-RM to induce muscle damage. Subjective rating of DOMS will be recorded at the completion of visit 2, and again at 24, 36, & 48 hours post visit 2. Participants will then be stratified into either a placebo or AX group based on their 48 hour DOMS score. Moreover, participants will return 48 hours later for visit 3 to complete a performance trial at 65, 70, and 75% of their 1-RM to failure. Participants will then supplement for 4-weeks and return for repeat testing (visits 4 and 5). ANTICIPATED RESULTS: Due to the anti-inflammatory effects reported from AX ingestion, we anticipate that AX will reduce the subjective reports of DOMS following a muscle damaging protocol and thus, subsequently improve performance as demonstrated by more repetitions to failure on the leg press.

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