Guillermo Pacheco, Danilo Tolusso, Whitley Stone, Shea Brgoch, Van Thuan Nguyen. Western Kentucky University, Bowling Green, KY.

BACKGROUND: The use of CBD as an alternative for pain management has increased in the last few years. CBD is purported to contain anti-inflammatory properties, decrease exercise induced muscle soreness, and reduce anxiety. Research has shown promising results in animal subjects; however, research with human participants is limited. Therefore, the purpose of this investigation was to evaluate the impact of two doses of CBD oil on performance and pain after an eccentric loading protocol. METHODS: Participants (n = 4) participated for three weeks, with a washout period between weeks. Baseline measurements included strength using handgrip dynamometry and bicep curl dynamometry and pain using a visual analog scale. At the beginning of each week, participants were subjected to a loading protocol of six sets of ten bicep curl eccentric only repetitions using a cable column. Participants consumed capsules of either a placebo, low dose (2mg/kg) or high dose (10mg/kg) of CBD oil immediately following the session and again twelve hours later. CBD supplementation continued every twelve hours for 48 hours. Outcome measures (handgrip strength, bicep curl strength, and pain) were repeated 24, 48, and 72 hours after each initial session. Data were analyzed using three by four repeated measure ANOVAs for condition and time. RESULTS: There were no differences in handgrip strength between conditions (F(2,6)=0.542, p =0.607, np2 = .153) or across time (F(3,9)= 2.235, p= .153, np2 = .427). There were no differences in bicep curl strength between conditions (F(2,6)= 0.675, p =0.554, np2 = .184) or across time (F(3,9)= 3.513, p= .150, np2 = .539). There were no differences in pain between conditions (F(2,6)= 0.495, p =0.633, np2 = .142), but there was a difference across time (F(3,9)= 7.028, p= .010, np2 = .701). There were no significant interactions to note. CONCLUSIONS: The chosen eccentric loading protocol was sufficient to cause delayed pain in participants. The CBD supplementation did not appear to make functional or pain related differences when compared to the placebo. However, observed effect sizes may indicate larger sample sizes are needed to identify differences between conditions. Future research should include larger sample sizes and implement eccentric exercise across a larger part of the body.

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