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Kailyn Lowder1, Lauren C. Bates-Fraser1,2,3, Lee Stoner1,2,4, FACSM, Erik D. Hanson1,2,3, FACSM 1. Department of Exercise and Sport Science. The University of North Carolina at Chapel Hill, Chapel Hill, NC. 2. Department of Allied Health Science. The University of North Carolina at Chapel Hill 3. Lineberger Comprehensive Cancer Center. The University of North Carolina at Chapel Hill 4. Department of Epidemiology. The University of North Carolina at Chapel Hill

BACKGROUND: Kidney cancer (KC) is the 10th most common cancer in the US, but given its 93% 5-year survival rate, there needs to be more emphasis on reducing chronic disease risk (i.e., cardiometabolic health) in the surviving population. Chronic disease risk may be mitigated through prescribing healthy 24-hour activity behaviors (24-AB), defined as sedentary (SB), moderate to vigorous physical activity (MVPA), and sleep behaviors over 24-hr. The objective of this study is to investigate 24-AB in KC survivors compared to survivors of other cancer types to identify future intervention targets specific to KC survivors. METHODS: From 2020-2022, we recruited an online convenience sample of 15 KC survivors (42 ± 18 years, 74% non-Hispanic, 87% white, 87% college degree, 47% income <$50,000) and 186 mixed-type cancer survivors (48 ± 19 years, 87% non-Hispanic, 74% white, 72% college degree, 83% income <$50,000). Participants self-reported 24-AB, including weekday SB (WD-SB), weekend SB (WE-SB), moderate-to-vigorous physical activity (MVPA), and sleep. A one-way ANOVA was used to compare 24-hour movement behaviors between KC survivors and mixed type survivors. Significance was set at p=0.05 and mean differences are reported. Cohen’s d was calculated to determine effect size determined as small (0.2), medium (0.5), and large (0.8). RESULTS: KC survivors reported significantly more WD-SB (3 hours, d=0.56, p = 0.02) and WE-SB (3 hours, d=0.69, p = 0.01) with medium effect sizes compared to mixed-type cancer survivors. There were no significant differences in MVPA (d=0.01) or sleep (d=0.44) between KC survivors and mixed type survivors (p > 0.05) with small and medium effect sizes respectively. CONCLUSIONS: KC survivors spend most of their time sitting and spend very minimal time being physically active, as they are not meeting recommended ACSM guidelines for MVPA, thus increasing their chronic disease risk. Compared to mixed-type cancer survivors, KC survivors engage in significantly more WD-SB and WE-SB. Therefore, future interventions aiming to improve 24-AB for KC survivors should target SB, however further research is needed to confirm these data with objective accelerometry data.

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