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THE EFFECT OF ASTAXANTHIN SUPPLEMENTATION ON SUBJECTIVE MARKERS OF MUSCLE SORENESS IN WOMEN.

Abstract

BACKGROUND: Strenuous exercise involving eccentric muscle actions induces skeletal muscle damage, resulting in delayed onset muscle soreness (DOMS). Antioxidant supplementation, such as astaxanthin (AX), may alleviate muscle injury following intense exercise. While previous research in males demonstrated that AX ingestion can reduce subjective measures of DOMS and possibly enhance aspects of endurance performance, to date, no studies have yet been conducted in a female only cohort. Therefore, the purpose of this study is to investigate the effect of AX supplementation at 12 mg/day-1 for 6-weeks on markers of physical performance and subjective markers of DOMS in females. METHODS: Participants will include 30, recreationally-active and healthy females (18-39 years), and the protocol will use a double-blinded, between-design (AX vs. placebo). Participants will complete four trials, with trials 1 and 3 designed to induce muscle damage (EIMD), consisting of a one-repetition maximum test (1RM) for leg-press, followed by five sets of ten repetitions at 65% of 1RM. Trials 2 and 4 will test exercise performance and will be conducted 48 h post-EIMD. Trials 2 and 4 will consist of sets at 65%, 70%, and 75% of 1RM to failure, with total repetitions completed included as our markers of physical performance. Subjective markers of DOMS will be collected using a visual analog scale and an algometer to test muscle tenderness 24, 36, & 48 h post EIMD. ANTICIPATED RESULTS: It is hypothesized that AX will reduce the subjective feelings of DOMS while possibly enhancing total repetitions completed due to a reduction in DOMS during trials 2 and 4. FUNDING: This study is funded by AstaReal USA.

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