Advisor(s) - Committee Chair
Thomas Coohill, Scott Ford, Frank Toman
Department of Biology
Master of Science
Ultraviolet light has previously been shown to cause viral induction in some SV40 transformed cell lines. The induction of this virus from an established line (clone E) of hamster kidney cells by monochromatic ultraviolet light was studied. Ten wavelengths in the region of 240 nm to 366 nm were tested. The induced viral titers were determined by the agar overlay plaque assay technique.
A distinct wavelength dependence was shown for induction in this cell-virus system. A broad peak in induction efficiency extending from 260 nm to 280 nm was found. This indicates a DNA-protein interaction in the induction process.
Biology | Life Sciences
Fry, Dennis, "The Wavelength Dependence of Ultraviolet Induction of Simian Virus 40 from a Transformed Line of Hamster Kidney Cells" (1978). Masters Theses & Specialist Projects. Paper 2361.