International Journal of Exercise Science 15(2): 1190-1201, 2022. While it has been demonstrated that acute resistance exercise (RE) alters measures of wave reflection and aortic arterial stiffness in young, healthy individuals, limited research has evaluated sex differences. Accordingly, we recruited moderately active, resistance-trained men (Age: 22 ± 3yrs, n=12) and women (23 ± 3yrs, n=10) to perform two randomized conditions consisting of an acute bout of weight machine RE or a quiet control (CON). Measures of aortic wave reflection and aortic stiffness were taken at baseline and 15 minutes following the RE (Recovery). At baseline, women had significantly higher heart rate (p = 0.05) and lower brachial systolic blood pressure (p = 0.009) compared to men. There were no significant three-way interactions for any variable. Significant condition by time interactions were noted for heart rate (Baseline: 65 ± 10bpm, Recovery: 87 ± 13bpm, p = 0.001), brachial systolic blood pressure (Baseline: 116 ± 9mmHg, Recovery: 123 ± 10mmHg, p = 0.014), and the augmentation index (AIx) normalized at 75bpm (Baseline: 7.7 ± 12.8%, Recovery: 15.5 ± 9.5%, p = 0.002) such that Recovery was augmented compared to Baseline following RE but not CON. There was also a significant main effect of time for augmentation pressure (Baseline: 4.1 ± 4.0mmHg, Recovery: 4.0 ± 3.6mmHg, p = 0.04) such that it decreased from Baseline to Recovery following RE but not the CON. There were no significant effects of sex, condition, or time on aortic arterial stiffness. Men and women have similar responses in measures of aortic wave reflection and aortic arterial stiffness following acute RE using weight machines.

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