Abstract
PURPOSE: Breast cancer (BC) treatment is associated with declines in physical activity, body composition, and physical function, as well as increased symptom burden. This case report examined effects of a patient-centered exercise and virtual reality (VR) mindfulness intervention initiated concurrently with chemotherapy on body composition, exercise endurance, and psychological well-being. METHODS: A 45-year-old female with BC participated in a 12-week exercise and VR mindfulness intervention initiated at the start of chemotherapy. Following PT assessment, an aerobic and resistance exercise program following the FITT format was progressed every 1-2 weeks based on treatment tolerance. Exercise adherence was tracked through activity logs and FitBit step counts. The VR mindfulness intervention used a Meta Oculus headset with Healium software and incorporated guided imagery and breathing exercises, with a goal of 60 minutes of practice weekly. Pre- and post-intervention assessments included vital signs, body composition (weight, % fat-free mass, % fat mass), cardiovascular endurance (3-minute step test and 6-minute walk test), and patient-reported outcomes including the Perceived Stress Scale, Five Facet Mindfulness Questionnaire, Patient Health Questionnaire (PHQ-15), and PROMIS Cancer measures. RESULTS: Body weight remained stable (74.4 vs. 74.8 kg), with minimal change in body fat percentage (35.7% vs. 35.8%). Self-reported activity level increased from light to moderate. Resting heart rate was unchanged, while blood pressure improved from 144/90 mmHg to 107/74 mmHg. Cardiovascular endurance was maintained during chemotherapy. Perceived stress decreased and mindfulness increased. PHQ-15 and several PROMIS measures worsened, consistent with treatment-related symptom progression. High adherence and satisfaction were reported. CONCLUSION: This case demonstrates the feasibility of combining individualized exercise and VR mindfulness during chemotherapy. Despite increased treatment-related symptoms, the participant maintained body composition and cardiovascular endurance while improving stress, mindfulness, and activity level. These findings support further evaluation of integrated exercise and mindfulness interventions during BC treatment.
Recommended Citation
Weiner, Luke; Martino, Sharon; and Warren, Kelly A.
(2026)
"Effects of a 12-Week Patient-Centered Exercise and Virtual Reality Mindfulness Intervention During Chemotherapy in a Breast Cancer Patient: A Case Report,"
International Journal of Exercise Science: Conference Proceedings: Vol. 15:
Iss.
9, Article 1.
Available at:
https://digitalcommons.wku.edu/ijesab/vol15/iss9/1