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THE EFFECTS OF ACUTE RAUWOLSCINE SUPPLEMENTATION ON ANAEROBIC EXERCISE PERFORMANCE

Abstract

Lenox Jones, Julianne Hill, Tanner Clark, Brendan Torres, Rebecca Rogers, Mallory Marshall, Courteney Benjamin, Christopher Ballmann, FACSM, Tyler Williams. Samford University, Birmingham, AL.

BACKGROUND: Rauwolscine is an alpha-2-adrenergic antagonist that is marketed as a performance enhancing supplement. Currently, there is a paucity of research on rauwolscine supplementation and exercise performance. The purpose of this study was to investigate the effects of acute rauwolscine supplementation on anaerobic exercise performance. METHODS: Eight resistance-trained males were recruited for this study. Using a double-blinded, counterbalanced, crossover design, subjects supplemented with either 2 mg of rauwolscine or a placebo (PL; gluten-free cornstarch) 30 minutes before anaerobic testing. During each trial, subjects completed 3 × 15 s Wingate Anaerobic Tests (WAnT) with a 2 min active recovery period between tests. Mean power, peak power, fatigue index, total work, and rating of perceived exertion (RPE) were recorded and analyzed. Additionally, blood lactate was measured prior to and immediately following the exercise tests. RESULTS: There was no difference in peak power (p=0.821), mean power (p=0.453), fatigue index (p=0.980), total work (p=0.429), and RPE (p=1.000). Blood lactate was higher during the rauwolscine trial compared to PL (p=0.050). CONCLUSION: Acute rauwolscine supplementation had no effect on anaerobic exercise performance and perceived exertion in resistance-trained males.

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