Limb-girdle muscular dystrophy is a rarely occurring disease not recognized in the past as a distinct entity. Prior to the advent of sophisticated molecular biology techniques in the early I 990s, precise diagnosis of the disease was impossible. However, identification of the altered proteins and underlying genetic defects has brought limb-girdle muscular dystrophy to the forefront of recent biomedical research. Many articles concerning the investigation into limb-girdle muscular dystrophy have been published in genetic and neuromuscular journals since 1992. These fmdings are individually significant, but only a few publications have compiled the results into a comprehensive article relating all past and present views. This paper attempts to review all the literature currently available and present it with less highly specialized scientific jargon than that used by the few authors who have recently published tutorials on limb-girdle muscular dystrophy.
Advisor(s) or Committee Chair
Dr. Blain Ferrel
Catlett, David N., "Autosomal Recessive Forms of Limb-Girdle Muscular Dystrophy" (1998). Mahurin Honors College Capstone Experience/Thesis Projects. Paper 208.