Advisor(s) - Committee Chair
Department of Biology
Master of Science
Some studies have reported in vitro inactivation of membrane enveloped viruses by Butylated hydroxytoluene (BHT). This study investigates the effect of orally administered BHT on primary infections of Herpes simplex virus (HSV) using rabbit corneas as the assay system.
Assigned levels of BHT were incorporated into the diet of New Zealand White rabbits with HSV-1 McKrae strain on the corneal surface of the eyes. The degree of infection was measured by a subjective assay. Rabbits receiving BHT in their diet consistently experienced lower levels of infection. The interpretation of this data is that orally administered BHT can be an effective inhibitor of primary infections by HSV in rabbits.
Biology | Diseases | Laboratory and Basic Science Research | Virus Diseases
Carson, Donald, "The Effect of Orally Administered Butylated Hydroxytoluene on Herpes Simplex Keratitis" (1983). Masters Theses & Specialist Projects. Paper 1376.